Vitexin exerts protective effects against calcium oxalate crystal-induced kidney pyroptosis in vivo and in vitro

Calcium oxalate crystals induce renal inflammation by NLRP3-mediated IL-1β secretion

Shrikant R. Mulay, Onkar P. Kulkarni, Khader Valli Rupanagudi et al. · Journal of Clinical Investigation · 2012 · 459 citations · Full text

Medicine, Immunology, Pathology +17

NLRP3 Inflammasome Activation‐Mediated Pyroptosis Aggravates Myocardial Ischemia/Reperfusion Injury in Diabetic Rats

Zhen Qiu, Shaoqing Lei, Bo Zhao et al. · Oxidative Medicine and Cellular Longevity · 2017 · 358 citations · Full text

Veterinary Medicine, Cardiology, Pathobiology +16

The macrophage phenotype and inflammasome component NLRP3 contributes to nephrocalcinosis-related chronic kidney disease independent from IL-1–mediated tissue injury

Hans‐Joachim Anders, Beatriz Suárez-Álvarez, Melissa Grigorescu et al. · Kidney International · 2017 · 217 citations · Full text

Medicine, Nephrology, Pathobiology +17

An NLRP3-specific inflammasome inhibitor attenuates crystal-induced kidney fibrosis in mice

Isis Ludwig‐Portugall, Eva Bartok, Ermanila Dhana et al. · Kidney International · 2016 · 191 citations · Full text

Medicine, Immunology, Pathology +14

Molecular mechanisms of crystal-related kidney inflammation and injury. Implications for cholesterol embolism, crystalline nephropathies and kidney stone disease

Shrikant R. Mulay, Andrew P. Evan, Hans‐Joachim Anders · Nephrology Dialysis Transplantation · 2013 · 186 citations

Medicine, Nephrology, Pathobiology +17