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An enzyme-free amplification strategy for sensitive assay of circulating tumor DNA based on wheel-like catalytic hairpin assembly and frame hybridization chain reaction

EngineeringBiochemistryNatural SciencesBioanalysisDna AnalysisOligonucleotideDna ReplicationMolecular BiologySynthetic BiologyNucleic Acid AmplificationTumor DnaDna ComputingMolecular DiagnosticsSensitive AssayEnzyme-free Amplification Strategy