Elucidation of the mechanism of NEFA-induced PERK-eIF2α signaling pathway regulation of lipid metabolism in bovine hepatocytes

Hepatic Fibroblast Growth Factor 21 Is Regulated by PPARα and Is a Key Mediator of Hepatic Lipid Metabolism in Ketotic States

Michael K. Badman, Pavlos Pissios, Adam R. Kennedy et al. · Cell Metabolism · 2007 · 1.5K citations · Full text

Metabolic Syndrome, Developmental Biology, Hepatology +15

ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1

Guenter Haemmerle, Tarek Moustafa, Gerald Woelkart et al. · Nature Medicine · 2011 · 740 citations · Full text

Biochemistry, Mitochondrial Function, Cell Signaling +13

GRP78 expression inhibits insulin and ER stress–induced SREBP-1c activation and reduces hepatic steatosis in mice

Hélène L. Kammoun, Hervé Chabanon, Isabelle Hainault et al. · Journal of Clinical Investigation · 2009 · 732 citations · Full text

Immunology, Er Stress, Fatty Liver Disease +25

Dephosphorylation of Translation Initiation Factor 2α Enhances Glucose Tolerance and Attenuates Hepatosteatosis in Mice

Seiichi Oyadomari, Heather P. Harding, Yuhong Zhang et al. · Cell Metabolism · 2008 · 430 citations · Full text

Enhances Glucose Tolerance, Attenuates Hepatosteatosis, Protein Expression +7

Inhibition of apolipoprotein B100 secretion by lipid-induced hepatic endoplasmic reticulum stress in rodents

Tsuguhito Ota, Constance Gayet, Henry N. Ginsberg · Journal of Clinical Investigation · 2008 · 365 citations · Full text