Artesunate ameliorates cigarette smoke-induced airway remodelling via PPAR-γ/TGF-β1/Smad2/3 signalling pathway

Oxidative stress–induced mitochondrial dysfunction drives inflammation and airway smooth muscle remodeling in patients with chronic obstructive pulmonary disease

Coen Wiegman, Charalambos Michaeloudes, Gulammehdi Haji et al. · Journal of Allergy and Clinical Immunology · 2015 · 431 citations · Full text

Activation of Peroxisome Proliferator-Activated Receptors in Human Airway Smooth Muscle Cells Has a Superior Anti-inflammatory Profile to Corticosteroids: Relevance for Chronic Obstructive Pulmonary Disease Therapy

Hema J Patel, Maria G. Belvisi, David Bishop‐Bailey et al. · The Journal of Immunology · 2003 · 134 citations · Full text

PPARγ agonists prevent TGFβ1/Smad3-signaling in human hepatic stellate cells

Caiyan Zhao, Wei Chen, Liu Yang et al. · Biochemical and Biophysical Research Communications · 2006 · 134 citations · Full text

Molecular Physiology, Hepatology, Signal Transduction +8

Activation of TGF-β/Smad2 signaling is associated with airway remodeling in asthma

Hironori Sagara, Takanori Okada, Ko Okumura et al. · Journal of Allergy and Clinical Immunology · 2002 · 128 citations · Full text

Inflammation, Asthma, Molecular Physiology +11

Side-Stream Cigarette Smoke Induces Dose–Response in Systemic Inflammatory Cytokine Production and Oxidative Stress

Zhang Jin, Yingying Liu, Jiaqi Shi et al. · Experimental Biology and Medicine · 2002 · 114 citations

Lipid Peroxidation, Immunology, Cardiovascular Toxicity +17