Jiaqi Shi

Macrophage-Released Pyrimidines Inhibit Gemcitabine Therapy in Pancreatic Cancer

Christopher J. Halbrook, Corbin Pontious, Ilya Kovalenko et al. · Cell Metabolism · 2019 · 402 citations · Full text

Oncology, Pancreatic Cancer, Medicine +4

NADP+-IDH Mutations Promote Hypersuccinylation that Impairs Mitochondria Respiration and Induces Apoptosis Resistance

Li Feng, Xiadi He, Dingwei Ye et al. · Molecular Cell · 2015 · 241 citations · Full text

Reductive Stress, Impairs Mitochondria Respiration, Induces Apoptosis Resistance +8

Inhibition of ATM Increases Interferon Signaling and Sensitizes Pancreatic Cancer to Immune Checkpoint Blockade Therapy

Qiang Zhang, Michael D. Green, Xueting Lang et al. · Cancer Research · 2019 · 234 citations · Full text

Immunology, Sensitizes Pancreatic Cancer, Immunotherapeutics +17

Tumour-reprogrammed stromal BCAT1 fuels branched-chain ketoacid dependency in stromal-rich PDAC tumours

Ziwen Zhu, Abhinav Achreja, Noah Meurs et al. · Nature Metabolism · 2020 · 193 citations · Full text

Tumor Biology, Oncogenic Agent, Ketoacid Dependency +8

BIN1 reverses PD-L1-mediated immune escape by inactivating the c-MYC and EGFR/MAPK signaling pathways in non-small cell lung cancer

J. Wang, Yunlong Jia, Sihai Zhao et al. · Oncogene · 2017 · 131 citations

Immunology, Bronchial Neoplasm, Immune Checkpoint Inhibitor +4