Concepedia

Design, synthesis and molecular docking of new pyrazole-thiazolidinones as potent anti-inflammatory and analgesic agents with TNF-α inhibitory activity

Somaia S. Abd El‐Karim, Hanaa S. Mohamed, Mohamed F. Abdelhameed, Abd El‐Galil E. Amr, Abdulrahman A. Almehizia, Eman S. Nossier

Bioorganic Chemistry · 2021 · 96 citations · 26 references

DOI

Concepts

References

26

Carrageenin-Induced Edema in Hind Paw of the Rat as an Assay for Antiinflammatory Drugs

C. A. Winter, Edwin A. Risley, George W. Nuss · Experimental Biology and Medicine · 1962 · 5.7K citations

, , +7

Inflammation 2010: New Adventures of an Old Flame

Ruslan Medzhitov · Cell · 2010 · 1.8K citations · Full text

, , +12

Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin

Diane Pennica, Glenn E. Nedwin, Joel S. Hayflick et al. · Nature · 1984 · 1.7K citations

, , +9

Small-Molecule Inhibition of TNF-α

Molly M. He, Annemarie Stroustrup, Johan D. Oslob et al. · Science · 2005 · 598 citations

, , +17

(–)-(1 R,2 R)-3-(3-Dimethylamino-1-ethyl-2-methyl-propyl)-phenol Hydrochloride (Tapentadol HCl): a Novel μ-Opioid Receptor Agonist/Norepinephrine Reuptake Inhibitor with Broad-Spectrum Analgesic Properties

Thomas Tzschentke, Thomas Christoph, Babette Kögel et al. · Journal of Pharmacology and Experimental Therapeutics · 2007 · 394 citations

, , +16