Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin

Diane Pennica, Glenn E. Nedwin, Joel S. Hayflick, +5

Nature

InflammationImmunotoxicologyPathogenesisImmunologyNecrosis Factor +7

Cloning and expression of human tissue-type plasminogen activator cDNA in E. coli

Diane Pennica, William E. Holmes, William J. Kohr, +9

Nature

E. ColiProtein ExpressionNatural SciencesVirulence FactorPathogenesis +9

The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog

Donna M. Stone, Mary Hynes, Mark Armanini, +11

Nature

Knockout MouseTumour-suppressor GeneSignal TransductionDevelopmental BiologySignaling Pathway +9

Disruption of the Jak1 Gene Demonstrates Obligatory and Nonredundant Roles of the Jaks in Cytokine-Induced Biologic Responses

Scott J. Rodig, Marco Antonio Meraz‐Ríos, J. Michael White, +9

Cell

InflammationCytokineSignal TransductionAutoimmune DiseaseReceptor Tyrosine Kinase +11

Expression of human immune interferon cDNA in E. coli and monkey cells

Patrick W. Gray, David W. M. Leung, Diane Pennica, +8

Nature

E. ColiAutoimmune DiseasePathogenesisImmunologyInnate Immune System +7

Ligand passing: the 75-kDa tumor necrosis factor (TNF) receptor recruits TNF for signaling by the 55-kDa TNF receptor.

Louis A. Tartaglia, Diane Pennica, David V. Goeddel

Journal of Biological Chemistry

Expression cloning of cardiotrophin 1, a cytokine that induces cardiac myocyte hypertrophy.

Diane Pennica, K. L. King, Kenneth J. Shaw, +7

Proceedings of the National Academy of Sciences

Cardiac MuscleHeart FailureExpression CloningCardiac Progenitor CellsCellular Physiology +20

Human Lymphotoxin and tumor necrosis factor genes: structure, homology and chromosomal localization

Glenn E. Nedwin, Susan L. Naylor, Alan Y. Sakaguchi, +5

Nucleic Acids Research

ImmunotoxicologyGeneticsInnate Immune SystemImmunologyPathology +21

<i>WISP</i> genes are members of the connective tissue growth factor family that are up-regulated in Wnt-1-transformed cells and aberrantly expressed in human colon tumors

Diane Pennica, Todd A. Swanson, James W. Welsh, +17

Proceedings of the National Academy of Sciences

PathologyWisp InductionCancer BiologyTumor BiologySignaling Pathway +15

Cloning and expression in Escherichia coli of the cDNA for murine tumor necrosis factor.

Diane Pennica, Joel S. Hayflick, Timothy S. Bringman, +2

Proceedings of the National Academy of Sciences

Active MutnfHuman TnfBacteriologyImmunologyPathology +16