Theranostics · 2021 · 31 citations · 32 references
EngineeringBiochemistryCardiologyCell SignalingRegenerative MedicineTissue EngineeringAngiogenesisCardiac RegenerationCardiac Tissue EngineeringCardiovascular PathophysiologyHeart DevelopmentVascular RegenerationEpicardial Cell ActivationMyocardial Infarction RepairMyocardial RegenerationMyocardial RepairMyocardial Tissue EngineeringSelf-assembling Peptide RepairSelf-assembling Peptide ScaffoldsTransgenic Mice
These results demonstrate that sustained release of Tβ4 from the functionalized SAP can activate the epicardium and effectively enhance the repair of infarcted myocardium. We believe the delivery of SAP-Tβ4 may be a promising strategy for MI therapy.
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Evidence for Cardiomyocyte Renewal in Humans
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Transient Regenerative Potential of the Neonatal Mouse Heart
Enzo R. Porrello, Ahmed I. Mahmoud, Emma Simpson et al. · Science · 2011 · 2.6K citations · Full text
Epicardial progenitors contribute to the cardiomyocyte lineage in the developing heart
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