Unique aspects of adaptive immunity in camelids and their applications

Chimeric Antigen Receptor–Modified T Cells in Chronic Lymphoid Leukemia

David L. Porter, Bruce L. Levine, Michael Kalos et al. · New England Journal of Medicine · 2011 · 3.5K citations · Full text

Chimeric Antigen Receptor, Chronic Lymphoid Leukemia, Autoimmune Disease +13

Naturally occurring antibodies devoid of light chains

C. Hamers‐Casterman, T. Atarhouch, Serge Muyldermans et al. · Nature · 1993 · 3.2K citations

Immunocytochemical Technique, Medicine, Immunology +5

Targeted delivery of a PD-1-blocking scFv by CAR-T cells enhances anti-tumor efficacy in vivo

Sarwish Rafiq, Oladapo Yeku, Hollie J. Jackson et al. · Nature Biotechnology · 2018 · 801 citations · Full text

Cancer Immunosurveillance, Pd-1-blocking Scfv, Immunology +9

A general protocol for the generation of Nanobodies for structural biology

Els Pardon, Toon Laeremans, Sarah Triest et al. · Nature Protocols · 2014 · 783 citations · Full text

Nanoarchitectonics, General Protocol, Engineering +11

Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies

Daniel Wrapp, Dorien De Vlieger, Kizzmekia S. Corbett et al. · Cell · 2020 · 650 citations · Full text

Vaccination, Virus Structure, Molecular Virology +8