Theranostics · 2021 · 63 citations · 0 references
Life SciencesMolecular BiologyPathobiologyInflammationProteomicsSignal TransductionInflammasome ActivationInflammatory SignalingNod-like ReceptorsPancreatic DiseasesPancreatic PathologyAcinar Cell DysfunctionAcinar Cell InjuryMolecular Docking Of InhibitorsNlr Family Pyrin Domain-containing 3 InflammasomeNlrp3 InflammasomePancreatic InjuryS100 Protein ExpressionS100 Proteins
Our study showed the important regulatory effect of S100A9 on pancreatic duct injury during AP and revealed that inhibition of the S100A9-VNN1 interaction may be a key therapeutic target for this disease.