Membrane Interactions of Virus-like Mesoporous Silica Nanoparticles

Sara Malekkhaiat Häffner, Elisa Parra‐Ortiz, Kathryn L. Browning, Elin Jørgensen, Maximilian W. A. Skoda, Costanza Montis, Xiaomin Li, Debora Berti, Dongyuan Zhao, Martin Malmsten

ACS Nano · 2021 · 111 citations · 47 references

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Abstract

bacteria. Taken together, these findings demonstrate that topography influences the interaction of nanoparticles with bacteria-mimicking lipid bilayers, both in the absence and presence of antimicrobial peptides, as well as with bacteria. The results also identify virus-like mesoporous nanoparticles as being of interest in the design of nanoparticles as delivery systems for antimicrobial peptides.

References

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