Concepedia

High-efficiency prime editing with optimized, paired pegRNAs in plants

Qiupeng Lin, Shuai Jin, Yuan Zong, Hong Yu, Zixu Zhu, Guanwen Liu, Liquan Kou, Yanpeng Wang, Jin‐Long Qiu, Jiayang Li,

Nature Biotechnology · 2021 · 324 citations · 18 references

DOI

Concepts

References

18

Search-and-replace genome editing without double-strand breaks or donor DNA

Andrew V. Anzalone, Peyton B. Randolph, Jessie R. Davis et al. · Nature · 2019 · 4.7K citations · Full text

, , +9

Unconstrained genome targeting with near-PAMless engineered CRISPR-Cas9 variants

Russell T. Walton, Kathleen A. Christie, Madelynn N. Whittaker et al. · Science · 2020 · 1.3K citations · Full text

, , +15

Prime genome editing in rice and wheat

Qiupeng Lin, Yuan Zong, Chenxiao Xue et al. · Nature Biotechnology · 2020 · 869 citations

, , +11

Efficient C-to-T base editing in plants using a fusion of nCas9 and human APOBEC3A

Yuan Zong, Qianna Song, Chao Li et al. · Nature Biotechnology · 2018 · 450 citations

, , +9

Predicting the efficiency of prime editing guide RNAs in human cells

Hui Kwon Kim · Nature Biotechnology · 2020 · 279 citations · Full text

, , +12