Converting primary tumor towards an in situ STING-activating vaccine via a biomimetic nanoplatform against recurrent and metastatic tumors

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

Hiroki Ishikawa, Glen N. Barber · Nature · 2008 · 3.4K citations · Full text

Inflammation, Host Response, Molecular Immunology +9

Calreticulin exposure dictates the immunogenicity of cancer cell death

Michel Obéid, Antoine Tesnière, François Ghiringhelli et al. · Nature Medicine · 2006 · 3K citations

Cancer Immunosurveillance, Calreticulin Exposure, Immunotoxicology +6

Toll-like receptor 4–dependent contribution of the immune system to anticancer chemotherapy and radiotherapy

Lionel Apétoh, François Ghiringhelli, Antoine Tesnière et al. · Nature Medicine · 2007 · 2.9K citations

Inflammation, Toll-like Receptors, Cancer Immunosurveillance +12

Cancer Cell Membrane-Coated Nanoparticles for Anticancer Vaccination and Drug Delivery

Ronnie H. Fang, Che‐Ming Jack Hu, Brian T. Luk et al. · Nano Letters · 2014 · 1.4K citations · Full text

Nanoparticles, Nanomedicine, Tumor Immunology +14

Autophagy induction via STING trafficking is a primordial function of the cGAS pathway

Xiang Gui, Hui Yang, Tuo Li et al. · Nature · 2019 · 1.2K citations · Full text

Mitophagy, Cellular Physiology, Cell Autophagy +16