Publication | Open Access
Drug Carriers: Classification, Administration, Release Profiles, and Industrial Approach
130
Citations
70
References
2021
Year
Medicinal ChemistryMedicineDrug ManufactureComplex WorldPharmaceutical TechnologyDrug Delivery SystemsBiomedical EngineeringDrug Release KineticsDrug Delivery SystemDrug CarriersPharmacologyIndustrial PharmacyRelease MechanismDrug DiscoveryPharmaceutical ResearchDrug Analysis
This work is aimed at providing a description of the complex world of drug carriers, starting from the description of this particular market in terms of revenue. Then, a brief overview of several types of conventional and innovative drug carrier systems has been included. The types of administration routes were also analyzed, with a critical and qualitative comment on drug release kinetics and drug profile shapes. Carriers were classified according to their ability to provide a prolonged and targeted release. The concept of the therapeutic window has been presented, providing advantages of having pulsed drug release to avoid side effects to target tissues. A critical comment on the use of conventional and innovative techniques for the production of drug carriers by large industrial companies has been proposed. As a final attempt for this work, an overall unique schematization of a drug carrier production process has been added, highlighting the necessity to create a strong double link among world-requested versatility of drug carriers for human applications and the newly developed industrial processes.
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