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Sirt6 protects cardiomyocytes against doxorubicin-induced cardiotoxicity by inhibiting P53/Fas-dependent cell death and augmenting endogenous antioxidant defense mechanisms

InflammationDoxorubicin-induced CardiotoxicityMedicineP53/fas-dependent Cell DeathApoptosisLipid PeroxidationCell DeathReactive Oxygen SpecieCardiovascular ToxicityPharmacologyCell BiologyOxidative Stress