Concepedia

TMEM52B suppression promotes cancer cell survival and invasion through modulating E-cadherin stability and EGFR activity

Yunhee Lee, Dongjoon Ko, Junghwa Yoon, Younghoon Lee, Semi Kim

Journal of Experimental & Clinical Cancer Research · 2021 · 15 citations · 25 references

DOIFull text

Open access

Abstract

These findings suggest that TMEM52B is a novel modulator of the interplay between E-cadherin and EGFR. It is possible that TMEM52B functions as a tumor-suppressor that could potentially be used as a novel prognostic marker for cancer.

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