ESBL-producing strains isolated from imported cases of enteric fever in England and Wales reveal multiple chromosomal integrations of <i>bla</i>CTX-M-15 in XDR <i>Salmonella</i> Typhi

Abstract

Chromosomal integration of blaCTX-M-15 within the XDR Sindh strains may lead to the maintenance of resistance in the absence of antibiotic selection pressure. Empirical treatment of cases of complicated enteric fever returning from Pakistan will henceforth have to include a carbapenem.