BKM120 sensitizes BRCA-proficient triple negative breast cancer cells to olaparib through regulating FOXM1 and Exo1 expression

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Transcriptional Regulation, Natural Sciences, Molecular Biology +6

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Combining a PI3K Inhibitor with a PARP Inhibitor Provides an Effective Therapy for BRCA1-Related Breast Cancer

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AKT/FOXO Signaling Enforces Reversible Differentiation Blockade in Myeloid Leukemias

Stephen M. Sykes, Steven Lane, Lars Bullinger et al. · Cell · 2011 · 256 citations · Full text

Hematological Malignancy, Mixed-phenotype Acute Leukemia, Myeloid Leukemias +5

Poly(ADP-ribose) polymerase-1 antagonizes DNA resection at double-strand breaks

Marie‐Christine Caron, Ajit Kumar Sharma, Julia O’Sullivan et al. · Nature Communications · 2019 · 178 citations · Full text