mBio · 2021 · 30 citations · 26 references
Life SciencesMicrobiologyBacteriologyInnate ImmunityMicrobial PathogenesisBacterial InfectionsBacterial PathogenesisPhagocyte BiologyAntimicrobial KillingBacillus SubtilisEscherichia ColiMicrobicidal MechanismsPhagocyte Antimicrobial ActivityPhagocytic Activity
, a model phagocytic cell amenable to genetic manipulations and quantitative analysis. Our results reveal that vastly different mechanisms are required to kill different species of bacteria. This very high degree of specificity was unexpected and indicates that a lot remains to be discovered about how phagocytic cells eliminate bacteria.
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Killing activity of neutrophils is mediated through activation of proteases by K+ flux
Emer P. Reeves, Hui Lu, Hugues Lortat Jacobs et al. · Nature · 2002 · 1.2K citations
Conserved developmental transcriptomes in evolutionarily divergent species
Anup Parikh, Edward Roshan Miranda, Mariko Katoh‐Kurasawa et al. · Genome biology · 2010 · 189 citations · Full text