mSphere · 2021 · 37 citations · 54 references
Life SciencesGeneticsMolecular BiologyEpigeneticsGene ExpressionTranscriptional RegulationAutophagy In ImmunityAutophagy ModulationAutophagy RegulationChromatinMacrophage BiologyPromoter RegulationAutophagy In Bacterial InfectionAutophagy In TuberculosisBacterial Autophagy ModulationMacrophage Transcriptional RegulationMycobacterium Tuberculosis InfectionMycobacterium Tuberculosis PathogenesisPathogen Inhibition
Drug-resistant TB is a serious challenge to TB control programs all over the world which calls for finding alternative therapeutic methods. Host-directed therapy is gaining significant momentum in treating infectious diseases. We propose that ZBTB25 is a potential target for host-directed treatment of TB.
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