The chromatin remodeler ISWI acts during <i>Drosophila</i> development to regulate adult sleep

Naihua N. Gong, Leela Chakravarti Dilley, Charlette Williams, Emilia H. Moscato, Milán Szuperák, Qin Wang, Matthew Jensen, Santhosh Girirajan, Tiong Yang Tan, Matthew A. Deardorff,

Science Advances · 2021 · 20 citations · 61 references

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Concepts

Abstract

patient variants fail to rescue sleep. We propose that sleep deficits are a primary phenotype of early developmental origin in NDDs and point toward chromatin remodeling machinery as critical for sleep circuit formation.

References

61