Concepedia

Treatment of influenza and SARS-CoV-2 infections via mRNA-encoded Cas13a in rodents

Emmeline L. Blanchard, Daryll Vanover, Swapnil Bawage, Pooja Tiwari, Laura Rotolo, Jared Beyersdorf, Hannah E. Peck, Nicholas C. Bruno, Robert Hincapie, Frank Michel,

Nature Biotechnology · 2021 · 237 citations · 33 references

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33

Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

Rafael Lozano, Mohsen Naghavi, Kyle J Foreman et al. · The Lancet · 2012 · 14.3K citations · Full text

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C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector

Omar O. Abudayyeh, Jonathan S. Gootenberg, Silvana Konermann et al. · Science · 2016 · 2.4K citations · Full text

, , +14

RNA targeting with CRISPR–Cas13

Omar O. Abudayyeh, Jonathan S. Gootenberg, Patrick Essletzbichler et al. · Nature · 2017 · 2.1K citations · Full text

, , +10

Pathogenesis and transmission of SARS-CoV-2 in golden hamsters

Sin Fun Sia, Li-Meng Yan, Alex W. H. Chin et al. · Nature · 2020 · 1.5K citations · Full text

, , +17

Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model

Thomas F. Rogers, Fangzhu Zhao, Deli Huang et al. · Science · 2020 · 1.5K citations · Full text

, , +17