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Fully defined human pluripotent stem cell-derived microglia and tri-culture system model C3 production in Alzheimer’s disease

Sudha R. Guttikonda, Lisa Sikkema, Jason Tchieu, Nathalie Saurat, Ryan Walsh, Oliver Harschnitz, Gabriele Ciceri, Marjolein A. M. Sneeboer, Linas Mažutis, Manu Setty,

Nature Neuroscience · 2021 · 250 citations · 58 references

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58

Genome engineering using the CRISPR-Cas9 system

F. Ann Ran, Patrick D. Hsu, Jason Wright et al. · Nature Protocols · 2013 · 11.7K citations · Full text

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SCANPY: large-scale single-cell gene expression data analysis

F. Alexander Wolf, Philipp Angerer, Fabian J. Theis · Genome biology · 2018 · 9.3K citations · Full text

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Neurotoxic reactive astrocytes are induced by activated microglia

Shane A. Liddelow, Kevin A. Guttenplan, Laura Clarke et al. · Nature · 2017 · 8K citations · Full text

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Spatial reconstruction of single-cell gene expression data

Rahul Satija, Jeffrey A. Farrell, David Gennert et al. · Nature Biotechnology · 2015 · 7.7K citations · Full text

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Resting Microglial Cells Are Highly Dynamic Surveillants of Brain Parenchyma in Vivo

Axel Nimmerjahn, Frank Kirchhoff, Fritjof Helmchen · Science · 2005 · 5.8K citations

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