Apigenin ameliorates doxorubicin-induced renal injury via inhibition of oxidative stress and inflammation

Abstract

APG has a protective role against DOX-induced nephrotoxicity, without weakening DOX cytotoxicity in malignant tumors. Thus, APG may serve as a potential protective agent against renal injury and inflammatory diseases and may be a promising candidate to attenuate renal toxicity in cancer patients treated with DOX.