Concepedia

Pentadecanoic acid promotes basal and insulin-stimulated glucose uptake in C2C12 myotubes

Wencheng Fu, Haiyan Li, Tiantian Li, Kuo Yang, Jiaxiang Chen, Sijia Wang, Chunhui Liu, Wen Zhang

Food & Nutrition Research · 2021 · 47 citations · 13 references

DOIFull text

Open access

Abstract

PA, an odd-chain SFA, significantly stimulates glucose uptake via the AMPK-AS160 pathway and exhibits an insulin-sensitizing effect in myotubes.

References

13

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα

Dario R. Alessi, Stephen R. James, C. Peter Downes et al. · Current Biology · 1997 · 2.8K citations · Full text

, , +11

Differences in the prospective association between individual plasma phospholipid saturated fatty acids and incident type 2 diabetes: the EPIC-InterAct case-cohort study

Nita G. Forouhi, Albert Koulman, Stephen J. Sharp et al. · The Lancet Diabetes & Endocrinology · 2014 · 542 citations · Full text

, , +9

Full intracellular retention of GLUT4 requires AS160 Rab GTPase activating protein

Lorena Eguez, Adrian Lee, Jose A. Chavez et al. · Cell Metabolism · 2005 · 307 citations · Full text

, , +9

Discovery of TBC1D1 as an Insulin-, AICAR-, and Contraction-stimulated Signaling Nexus in Mouse Skeletal Muscle

Eric B. Taylor, An Ding, Henning F. Kramer et al. · Journal of Biological Chemistry · 2008 · 269 citations · Full text

, , +11

The Rab GTPase-Activating Protein AS160 Integrates Akt, Protein Kinase C, and AMP-Activated Protein Kinase Signals Regulating GLUT4 Traffic

Farah S. L. Thong, Philip J. Bilan, Amira Klip · Diabetes · 2007 · 239 citations · Full text