Concepedia

Sorafenib not only impairs endothelium-dependent relaxation but also promotes vasoconstriction through the upregulation of vasoconstrictive endothelin type B receptors

Qi Yu, Kun Li, Andong Zhao, Mengqian Wei, Zhenhao Huang, Yunting Zhang, Ying Chen, Ting Lian, Chuan Wang, Li Xu,

Toxicology and Applied Pharmacology · 2021 · 13 citations · 19 references

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References

19

Metformin Protects Endothelial Function in Diet-Induced Obese Mice by Inhibition of Endoplasmic Reticulum Stress Through 5′ Adenosine Monophosphate–Activated Protein Kinase–Peroxisome Proliferator–Activated Receptor δ Pathway

Wai San Cheang, Xiao Yu Tian, Wing Tak Wong et al. · Arteriosclerosis Thrombosis and Vascular Biology · 2014 · 179 citations · Full text

Inhibition of Tumor Endothelial ERK Activation, Angiogenesis, and Tumor Growth by Sorafenib (BAY43-9006)

Danielle Murphy, Sosina Makonnen, Wiem Lassoued et al. · American Journal Of Pathology · 2006 · 156 citations · Full text

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ROS-mediated JNK/p38-MAPK activation regulates Bax translocation in Sorafenib-induced apoptosis of EBV-transformed B cells

Ga Bin Park, Yunock Choi, Yeong Seok Kim et al. · International Journal of Oncology · 2014 · 96 citations · Full text

, , +17

Overcoming sorafenib evasion in hepatocellular carcinoma using CXCR4-targeted nanoparticles to co-deliver MEK-inhibitors

Yunching Chen, Ya-Chi Liu, Yun‐Chieh Sung et al. · Scientific Reports · 2017 · 81 citations · Full text

Role of ERK/MAPK in endothelin receptor signaling in human aortic smooth muscle cells

Qing-wen Chen, Lars Edvinsson, Cang‐Bao Xu · BMC Cell Biology · 2009 · 74 citations · Full text