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Pyrazolo[3,4-d]pyrimidine-based dual EGFR T790M/HER2 inhibitors: Design, synthesis, structure–activity relationship and biological activity as potential antitumor and anticonvulsant agents

Biological ActivityMolecular PharmacologyMedicinal ChemistryStructure–activity RelationshipPotential AntitumorMedicineNatural SciencesRational Drug DesignPharmacological AgentPharmacotherapyAnti-cancer AgentDrug DevelopmentPharmacologyRadiation OncologyPharmaceutical ChemistryTumor BiologyDrug Discovery