Visible light-mediated cross-coupling of electrophiles: synthesis of α-amino amides from isocyanates and ketimines

Abstract

Cross-couplings between the electrophilic ketimines and isocyanates are achieved <italic>via</italic> the visible light-mediated reactivity inversion of the ketimines, affording the desired α-amino amides in high yields, with both metal and metal-free systems.