The Alleviative Effects of Quercetin on Cadmium-Induced Necroptosis via Inhibition ROS/iNOS/NF-κB Pathway in the Chicken Brain

RIP1 autophosphorylation is promoted by mitochondrial ROS and is essential for RIP3 recruitment into necrosome

Yingying Zhang, Sheng Sean Su, Shubo Zhao et al. · Nature Communications · 2017 · 600 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

Quercetin disrupts tyrosine-phosphorylated phosphatidylinositol 3-kinase and myeloid differentiation factor-88 association, and inhibits MAPK/AP-1 and IKK/NF-κB-induced inflammatory mediators production in RAW 264.7 cells

Mehari Endale, Seung‐Chun Park, Suk Kim et al. · Immunobiology · 2013 · 273 citations

Life Sciences, Immunology, Pharmacology +16

Toxin-Induced Necroptosis Is a Major Mechanism of Staphylococcus aureus Lung Damage

Kipyegon Kitur, Dane Parker, Pamela A. Nieto et al. · PLoS Pathogens · 2015 · 264 citations · Full text

Life Sciences, Microbiology, Pathobiology +17

Reactive oxygen species regulate Smac mimetic/TNFα-induced necroptotic signaling and cell death

Barbara Schenk, Simone Fulda · Oncogene · 2015 · 237 citations

Life Sciences, Cell Biology, Pathobiology +16

Quercetin prevents necroptosis of oligodendrocytes by inhibiting macrophages/microglia polarization to M1 phenotype after spinal cord injury in rats

Hong Fan, Hai‐Bin Tang, Lequn Shan et al. · Journal of Neuroinflammation · 2019 · 226 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17