Concepedia

Semisynthesis and biological evaluation of a focused library of unguinol derivatives as next-generation antibiotics

M. T. Morshed, Nguyen Thi Thu Hang, Daniel Vuong, Andrew Crombie, Ernest Lacey, Abiodun D. Ogunniyi, Stephen W. Page, Darren J. Trott, Andrew M. Piggott

Organic & Biomolecular Chemistry · 2021 · 14 citations · 26 references

DOI

Concepts

Abstract

Semisynthetic unguinol derivatives showed potent activity against a panel of methicillin-resistant <italic>Staphylococcus aureus</italic> strains and are promising candidates for further development.

References

26

Performance standards for antimicrobial susceptibility testing

Mary Jane Ferraro · 2001 · 9.8K citations

, , +11

A new antibiotic kills pathogens without detectable resistance

Losee L. Ling, Tanja Schneider, Aaron J. Peoples et al. · Nature · 2015 · 2.4K citations · Full text

, , +12

Use of Ichip for High-Throughput <i>In Situ</i> Cultivation of “Uncultivable” Microbial Species

Dominica Nichols, N. Cahoon, E. M. Trakhtenberg et al. · Applied and Environmental Microbiology · 2010 · 726 citations · Full text

, , +12

Antibiotic Substances From Basidiomycetes

Frederick Kavanagh, Annette Hervey, William J. Rôbbins · Proceedings of the National Academy of Sciences · 1951 · 347 citations · Full text

, , +17

The Schenck Ene Reaction: Diastereoselective Oxyfunctionalization with Singlet Oxygen in Synthetic Applications

Michael Prein, Waldemar Adam · Angewandte Chemie International Edition in English · 1996 · 329 citations

, , +17