Concepedia

Design, synthesis, and evaluation of liver-specific gemcitabine prodrugs for potential treatment of hepatitis C virus infection and hepatocellular carcinoma

Anthony A. Stephenson, Sheng Cao, David J. Taggart, Vinod P. Vyavahare, Zucai Suo

European Journal of Medicinal Chemistry · 2021 · 15 citations · 39 references

DOI

Concepts

References

39

Cancer statistics, 2015

Rebecca L. Siegel, Kimberly D. Miller, Ahmedin Jemal · CA A Cancer Journal for Clinicians · 2015 · 11.9K citations · Full text

Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial.

Howard A. Burris, Malcolm J. Moore, John Sahl Andersen et al. · Journal of Clinical Oncology · 1997 · 5.8K citations

Action of 2',2'-difluorodeoxycytidine on DNA synthesis.

Peng Huang, Sherri Chubb, Larry W. Hertel et al. · PubMed · 1991 · 884 citations

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Gemcitabine: metabolism, mechanisms of action, and self-potentiation.

William Plunkett, Peng Huang, Yi-Zheng Xu et al. · PubMed · 1995 · 756 citations

Gemcitabine: preclinical pharmacology and mechanisms of action.

William Plunkett, Peng Huang, C. E. Searcy et al. · PubMed · 1996 · 395 citations