Concepedia

Publication | Open Access

PTEN deficiency leads to proteasome addiction: a novel vulnerability in glioblastoma

DOIFull Paper Access

42

Citations

34

References

2021

Year

Jorge A. Benítez, Darren Finlay, Anthony S. Castanza, Alison D. Parisian, Jianhui Ma, Ciro Longobardi, Alex Campos, Raghavendra Vadla, Alejandro Izurieta, Gianluca Scerra,
Neuro-Oncology

Abstract

Proteasome inhibition is a potential synthetic lethal therapeutic strategy for GBM with proteasome addiction due to a high protein synthesis rate and autophagy deficiency.

References

YearCitations

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