Anthony S. Castanza

mTOR Inhibition Alleviates Mitochondrial Disease in a Mouse Model of Leigh Syndrome

Simon C. Johnson, Melana E. Yanos, Ernst‐Bernhard Kayser et al. · Science · 2013 · 547 citations

Life Sciences, Molecular Biology, Neuroscience +14

A Comprehensive Analysis of Replicative Lifespan in 4,698 Single-Gene Deletion Strains Uncovers Conserved Mechanisms of Aging

Mark A. McCormick, Joe R. Delaney, Mitsuhiro Tsuchiya et al. · Cell Metabolism · 2015 · 270 citations · Full text

Education, Genetics, Molecular Genetics +12

Molecular mechanisms underlying genotype‐dependent responses to dietary restriction

Jennifer Schleit, Simon C. Johnson, Christopher F. Bennett et al. · Aging Cell · 2013 · 174 citations · Full text

Life Sciences, Biology, Genetics +17

Dose-dependent effects of mTOR inhibition on weight and mitochondrial disease in mice

Simon C. Johnson, Melana E. Yanos, Alessandro Bitto et al. · Frontiers in Genetics · 2015 · 94 citations · Full text

Life Sciences, Pharmacology, Pharmacotherapy +16

Stress profiling of longevity mutants identifies <scp>Afg3</scp> as a mitochondrial determinant of cytoplasmic <scp>mRNA</scp> translation and aging

Joe R. Delaney, Umema Ahmed, Annie Chou et al. · Aging Cell · 2012 · 71 citations · Full text

Life Sciences, Genetics, Molecular Biology +17