Concepedia

Design of Experiments (DoE) - Based Enhanced Quality by Design Approach to Hydrolytic Degradation Kinetic Study of Capecitabine by Eco-friendly Stability Indicating UV-Visible Spectrophotometry

Pintu Prajapati, Radhika Patel, Dilan Patel, Shailesh Shah

American Journal of PharmTech Research · 2020 · 21 citations · 6 references

DOIFull text

Open access

Concepts

Abstract

Capecitabine is an anti-metabolite class of anti-neoplastic drug that is converted to fluorouracil in body tissue. Numbers of stability indicating chromatography method such as HPLC, HPTLC etc.

References

6

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A new, validated HPLC‐MS/MS method for the simultaneous determination of the anti‐cancer agent capecitabine and its metabolites: 5′‐deoxy‐5‐fluorocytidine, 5′‐deoxy‐5‐fluorouridine, 5‐fluorouracil and 5‐fluorodihydrouracil, in human plasma

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An APCI LC‐MS/MS method for routine determination of capecitabine and its metabolites in human plasma

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A rapid and simple HPTLC assay for therapeutic drug monitoring of capecitabine in colorectal cancer patients

Sonali G. Thorat, Rupesh V. Chikhale, Madhukar Tajne · Biomedical Chromatography · 2017 · 13 citations

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Development and validation of an ecofriendly HPLC-UV method for determination of capecitabine in human plasma: Application to pharmacokinetic studies

Sepideh Hassanlou, Mehdi Rajabi, A. Shahrasbi et al. · South African Journal of Chemistry · 2016 · 12 citations · Full text

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