A DNA structure-mediated fluorescent biosensor for apurinic/apyrimidinic endonuclease 1 activity detection with ultra-high sensitivity and selectivity

APE1/Ref-1 Interacts with NPM1 within Nucleoli and Plays a Role in the rRNA Quality Control Process

Carlo Vascotto, Damiano Fantini, Milena Romanello et al. · Molecular and Cellular Biology · 2009 · 242 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Isolation of a small molecule inhibitor of DNA base excision repair

Srinivasan Madhusudan, Frank W. Smart, Paul J. Shrimpton et al. · Nucleic Acids Research · 2005 · 238 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +16

Elevated and altered expression of the multifunctional DNA base excision repair and redox enzyme Ape1/ref-1 in prostate cancer.

Mark R. Kelley, Lan Cheng, Richard S. Foster et al. · PubMed · 2001 · 194 citations

Life Sciences, Molecular Biology, Oncology +17

APE1 overexpression is associated with cisplatin resistance in non-small cell lung cancer and targeted inhibition of APE1 enhances the activity of cisplatin in A549 cells

Dong Wang, Xueqin Yang, Liansheng Chen et al. · Lung Cancer · 2009 · 191 citations

Medicine, Oncology, Pharmacology +9

Detection of nicking endonuclease activity using a G-quadruplex-selective luminescent switch-on probe

Lihua Lu, Daniel Shiu‐Hin Chan, Daniel W. J. Kwong et al. · Chemical Science · 2014 · 142 citations

Life Sciences, Biochemistry, Molecular Biology +15