Publication | Open Access
IL-6 levels are dramatically high in the sputum from children with sickle cell disease during acute chest syndrome
19
Citations
14
References
2020
Year
Acute Lung InjuryInflammatory Lung DiseaseLung InflammationImmunodeficienciesImmunologyAcute Chest SyndromeInflammationHematologyInflammatory MarkerRespiratory InfectionAcute MedicineIl-6 LevelsRespiratory DiseasesAnti–il-6 TrialsPulmonary MedicineSickle Cell DiseaseInborn Error Of ImmunityPulmonary DiseaseInflammatory CellsInfectious Respiratory DiseaseMedicine
Key Points Sputum interleukin-6 (IL-6) level is high during acute chest syndrome (ACS) in pediatric sickle cell disease, supporting anti–IL-6 trials. Sputum IL-8, CCL2, and CCL3 levels are also high during ACS, possibly contributing to recruitment of inflammatory cells in the lungs.
| Year | Citations | |
|---|---|---|
Page 1
Page 1