Microglial depletion and repopulation: a new era of regenerative medicine?

Orally administered colony stimulating factor 1 receptor inhibitor PLX3397 in recurrent glioblastoma: an Ivy Foundation Early Phase Clinical Trials Consortium phase II study

Nicholas Butowski, Howard Colman, John de Groot et al. · Neuro-Oncology · 2015 · 580 citations · Full text

Medicine, Oncology, Pharmacology +17

Replacement of microglia in the aged brain reverses cognitive, synaptic, and neuronal deficits in mice

Monica R. P. Elmore, Lindsay A. Hohsfield, Enikö A. Kramár et al. · Aging Cell · 2018 · 394 citations · Full text

Medicine, Neurobiology, Neuroscience +17

Depletion of microglia exacerbates postischemic inflammation and brain injury

Wei-Na Jin, Samuel Shi, Zhiguo Li et al. · Journal of Cerebral Blood Flow & Metabolism · 2017 · 371 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Microglial Depletion with CSF1R Inhibitor During Chronic Phase of Experimental Traumatic Brain Injury Reduces Neurodegeneration and Neurological Deficits

Rebecca J. Henry, Rodney M. Ritzel, James P. Barrett et al. · Journal of Neuroscience · 2020 · 343 citations · Full text

Medicine, Neurobiology, Neuroscience +17

Elimination of Microglia Improves Functional Outcomes Following Extensive Neuronal Loss in the Hippocampus

Rachel Rice, Elizabeth E. Spangenberg, Hana Yamate-Morgan et al. · Journal of Neuroscience · 2015 · 294 citations · Full text

Medicine, Neurobiology, Neuroscience +16