Simvastatin accelerates the healing process of burn wound in Wistar rats through Akt/mTOR signaling pathway

Specificity and mechanism of action of some commonly used protein kinase inhibitors

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Drug Target, Pharmacotherapy, Pharmaceutical Chemistry +17

Specificity and mechanism of action of some commonly used protein kinase inhibitors

Stephen Davies, Helen Reddy, Matilde Caivano et al. · Biochemical Journal · 2000 · 3.1K citations

Drug Target, Pharmacotherapy, Pharmaceutical Chemistry +17

The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals.

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Phosphoinositide 3-Kinase Signaling to Akt Promotes Keratinocyte Differentiation Versus Death

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Skin Development, Phosphoinositide 3-Kinase, Signal Transduction +13

Ginkgolic Acid Inhibits Invasion and Migration and TGF‐β‐Induced EMT of Lung Cancer Cells Through PI3K/Akt/mTOR Inactivation

Seung Ho Baek, Jeong‐Hyeon Ko, Jong Hyun Lee et al. · Journal of Cellular Physiology · 2016 · 216 citations

Chemoprevention Strategy, Immunology, Cancer Biology +16