Concepedia

SHP-1 Regulates Antigen Cross-Presentation and Is Exploited by Leishmania to Evade Immunity

Sofía C. Khouili, Emma C. L. Cook, Elena Hernández‐García, María Martínez‐López, Ruth Conde‐Garrosa, Salvador Iborra

Cell Reports · 2020 · 25 citations · 36 references

DOIFull text

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Concepts

Abstract

cell-based vaccination against the parasite. Thus, SHP-1-mediated impairment of cross-presentation can be exploited by pathogens to evade CTLs, and SHP-1 inhibition improves CTL responses during vaccination.

References

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