RSC Medicinal Chemistry · 2020 · 19 citations · 26 references
PharmacyOncologyPharmacologyDrug DeliveryNanoparticle Drug DeliveryTargeted Drug DeliveryActive TargetingCancer NanomedicineNanomedicinePhotodynamic TherapyTargeted Cancer TherapyTargeted TherapyActive Tumor TargetingCancer Photodynamic TherapyEpidermal Growth Factor Receptor Targeting LigandsMolecular TargetingPhotodynamic Therapy NanomaterialsPhotosensitizersPhototoxicityTumor-targeted Drug Delivery
Gold nanoparticles, covalently functionalised with the photosensitiser C11Pc and PEG, were actively targeted towards epidermal growth factor receptor overexpressing cancers using the peptide FITC-βAAEYLRK. Selective phototoxicity was observed at nanomolar concentrations with minimal dark toxicity.
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Gold Nanoparticles Are Taken Up by Human Cells but Do Not Cause Acute Cytotoxicity
Ellen E. Connor, Judith N. Mwamuka, Anand Gole et al. · Small · 2005 · 2.4K citations
Photosensitizers in clinical PDT
Ron R. Allison, Gordon Downie, Rosa Cuenca et al. · Photodiagnosis and Photodynamic Therapy · 2004 · 1K citations