Concepedia

Publication | Open Access

Intestinal Dysbiosis Amplifies Acetaminophen-Induced Acute Liver Injury

DOIFull Paper Access

98

Citations

53

References

2020

Year

Kai Markus Schneider, Carsten Elfers, Ahmed Ghallab, Carolin V. Schneider, Eric J. C. Gálvez, Antje Mohs, Wenfang Gui, Lena Susanna Candels, Theresa H. Wirtz, Sebastian Zuehlke,
Cellular and Molecular Gastroenterology and Hepatology

Abstract

Our data show an important yet unknown function of intestinal microbiota during ALF. Intestinal dysbiosis was transferrable to healthy WT mice via FMT and aggravated liver injury. Our study highlights intestinal microbiota as a targetable risk factor for ALF.

References

YearCitations

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