Reduced sensitivity of <scp>PLASMIC</scp> and <scp>French</scp> scores for the diagnosis of thrombotic thrombocytopenic purpura in older individuals

Abstract

The PLASMIC and French TTP scores have reduced sensitivity at age ≥ 60 years and are less reliable in identifying TTP in older patients. A high index of suspicion and availability of rapid ADAMTS13 assays is required to correctly diagnose all patients with TTP.