Curcumin steers THP-1 cells under LPS and mTORC1 challenges toward phenotypically resting, low cytokine-producing macrophages

Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR Complex

Dos D. Sarbassov, David A. Guertin, Siraj M. Ali et al. · Science · 2005 · 6.2K citations

Life Sciences, Cell Biology, Molecular Biology +17

Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions.

Ann‐Lii Cheng, Chih‐Hung Hsu, Jen‐Kou Lin et al. · PubMed · 2001 · 2.1K citations

Medicine, Oncology, Pharmacology +10

Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer

Arkaitz Carracedo, Li Ma, Julie Teruya‐Feldstein et al. · Journal of Clinical Investigation · 2008 · 1.4K citations · Full text

Medicine, Oncology, Pharmacology +17

Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40

Emilie Vander Haar, Seong-il Lee, Sricharan Bandhakavi et al. · Nature Cell Biology · 2007 · 1.2K citations

Life Sciences, Cell Biology, Molecular Biology +12

CD68/macrosialin: not just a histochemical marker

Dimitry A. Chistiakov, M. Killingsworth, Veronika A. Myasoedova et al. · Laboratory Investigation · 2016 · 733 citations · Full text

Life Sciences, Immunology, Pathology +16