Concepedia

Exogenous bone marrow derived-putative endothelial progenitor cells attenuate ischemia reperfusion-induced vascular injury and renal fibrosis in mice dependent on pericytes

Meng Wang, Huzi Xu, Yinzheng Li, Chujin Cao, Han Zhu, Zhi Zhao, Guangchang Pei, Fan Zhu, Qian Yang, Xuan Deng,

Theranostics · 2020 · 24 citations · 29 references

DOIFull text

Open access

Concepts

Abstract

Exogenous b-pEPCs directly protect against IR-induced vascular injury and prevent renal fibrosis by inhibiting the activation of PDGFR-β-positive pericytes.

References

29

Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1

Daniel J. Ceradini, Anita R. Kulkarni, Matthew J. Callaghan et al. · Nature Medicine · 2004 · 2.6K citations

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Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury

Li Yang, Tatiana Y. Besschetnova, Craig R. Brooks et al. · Nature Medicine · 2010 · 1.3K citations · Full text

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Exosomes From Human CD34 <sup>+</sup> Stem Cells Mediate Their Proangiogenic Paracrine Activity

Susmita Sahoo, Ekaterina Klychko, Tina Thorne et al. · Circulation Research · 2011 · 598 citations · Full text

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Microvesicles derived from endothelial progenitor cells protect the kidney from ischemia–reperfusion injury by microRNA-dependent reprogramming of resident renal cells

Vincenzo Cantaluppi, Stefano Gatti, Davide Medica et al. · Kidney International · 2012 · 544 citations · Full text

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Pericyte-expressed Tie2 controls angiogenesis and vessel maturation

Martin Teichert, Laura Milde, Annegret Holm et al. · Nature Communications · 2017 · 356 citations · Full text

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