Hypoxia-induced GPR4 suppresses trophoblast cell migration and proliferation through the MAPK signaling pathway

Acidosis Activates Endoplasmic Reticulum Stress Pathways through GPR4 in Human Vascular Endothelial Cells

Lixue Dong, Elizabeth A. Krewson, Li V. Yang · International Journal of Molecular Sciences · 2017 · 131 citations · Full text

Endothelial Cells, Immunology, Er Stress/upr +23

Inhibition of tumor cell migration and metastasis by the proton-sensing GPR4 receptor

Reid D. Castellone, Nancy R. Leffler, Lixue Dong et al. · Cancer Letters · 2011 · 103 citations

Tumor Biology, G Protein-coupled Receptor, Medicine +10

Previously postulated “ligand-independent” signaling of GPR4 is mediated through proton-sensing mechanisms

Masayuki Tobo, Hideaki Tomura, Chihiro Mogi et al. · Cellular Signalling · 2007 · 94 citations

Molecular Physiology, Signal Transduction, Biochemistry +10

Reduced pathological angiogenesis and tumor growth in mice lacking GPR4, a proton sensing receptor

Lorenza Wyder, Thomas Suply, Bérangère Ricoux et al. · Angiogenesis · 2011 · 93 citations

Angiogenesis, G Protein-coupled Receptor, Tumor Growth +8

The Proton-activated Receptor GPR4 Modulates Intestinal Inflammation

Yu Wang, Cheryl de Vallière, Pedro Henrique Imenez Silva et al. · Journal of Crohn s and Colitis · 2017 · 84 citations · Full text