Xanthohumol attenuates isoprenaline-induced cardiac hypertrophy and fibrosis through regulating PTEN/AKT/mTOR pathway

Integrin β3 promotes cardiomyocyte proliferation and attenuates hypoxia-induced apoptosis via regulating the PTEN/Akt/mTOR and ERK1/2 pathways

Lijiang Wei, Qingqing Zhou, Hua Tian et al. · International Journal of Biological Sciences · 2020 · 146 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

The Tumor Suppressor Gene PTEN Can Regulate Cardiac Hypertrophy and Survival

Gary Schwartzbauer, Jeffrey Robbins · Journal of Biological Chemistry · 2001 · 144 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Human pharmacokinetics of xanthohumol, an antihyperglycemic flavonoid from hops

LeeCole Legette, Chanida Karnpracha, Ralph L. Reed et al. · Molecular Nutrition & Food Research · 2013 · 136 citations

Pharmacy, Pharmacokinetics, Pharmacology +11

Isoproterenol-Induced Heart Failure in the Rat is Associated with Nitric Oxide-Dependent Functional Alterations of Cardiac Function

Peter Křenek, Jana Kmecova, Dana Kučerová et al. · European Journal of Heart Failure · 2009 · 120 citations · Full text

Life Sciences, Pharmacology, Physiology +13

Pharmacokinetics of prenylated hop phenols in women following oral administration of a standardized extract of hops

Richard B. van Breemen, Yuan Yang, Suzanne Banuvar et al. · Molecular Nutrition & Food Research · 2014 · 112 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +11