Ca2+ Release via IP3 Receptors Shapes the Cardiac Ca2+ Transient for Hypertrophic Signaling

Variance based sensitivity analysis of model output. Design and estimator for the total sensitivity index

Andrea Saltelli, Paola Annoni, Ivano Azzini et al. · Computer Physics Communications · 2009 · 3.3K citations

Computing, Systems Engineering, Optimization +14

A Calcineurin-Dependent Transcriptional Pathway for Cardiac Hypertrophy

Jeffery D. Molkentin, Jianrong Lu, Christopher L. Antos et al. · Cell · 1998 · 2.6K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Differential activation of transcription factors induced by Ca2+ response amplitude and duration

Ricardo E. Dolmetsch, Richard S. Lewis, Christopher C. Goodnow et al. · Nature · 1997 · 1.7K citations

Life Sciences, Cell Biology, Molecular Biology +16

Differential activation of transcription factors induced by Ca2+ response amplitude and duration

Ricardo E. Dolmetsch, Richard S. Lewis, Christopher C. Goodnow et al. · Nature · 1997 · 1.5K citations

Life Sciences, Cell Biology, Molecular Biology +16

Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death

Peter J. Mohler, Jean‐Jacques Schott, Anthony O. Gramolini et al. · Nature · 2003 · 960 citations

Medicine, Cardiology, Genetics +15