Efficacy of a novel double-controlled oncolytic adenovirus driven by the Ki67 core promoter and armed with IL-15 against glioblastoma cells

Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth

Wenchao Zhou, Susan Q. Ke, Zhi Huang et al. · Nature Cell Biology · 2015 · 971 citations · Full text

Neuro-oncology, Glioblastoma Stem Cells, Health Sciences +12

Glioblastoma Stem Cells Generate Vascular Pericytes to Support Vessel Function and Tumor Growth

Lin Cheng, Zhi Huang, Wenchao Zhou et al. · Cell · 2013 · 871 citations · Full text

Developmental Biology, Angiogenesis, Medicine +10

Glioma cancer stem cells induce immunosuppressive macrophages/microglia

Adam Wu, Jun Wei, Ling-Yuan Kong et al. · Neuro-Oncology · 2010 · 693 citations · Full text

Immunology, Immune Regulation, Immunologic Mechanism +25

HRG Inhibits Tumor Growth and Metastasis by Inducing Macrophage Polarization and Vessel Normalization through Downregulation of PlGF

Charlotte Rolny, Massimiliano Mazzone, Sònia Tugues et al. · Cancer Cell · 2011 · 692 citations · Full text

Angiogenesis, Immunology, Cell Proliferation +10

Phase I Study of DNX-2401 (Delta-24-RGD) Oncolytic Adenovirus: Replication and Immunotherapeutic Effects in Recurrent Malignant Glioma

Frederick F. Lang, Charles A. Conrad, Candelaria Gomez‐Manzano et al. · Journal of Clinical Oncology · 2018 · 672 citations · Full text