A hepatocyte-targeting fluorescent probe for imaging isoniazid-induced hydrazine in HepG2 cells and zebrafish

Zhenbo Guo, Mei Wang, Xueyan Li, Xu Jia, Xiaoli Wang, Pingzhu Zhang, Chao Wei, Xiaoliu Li

Chemical Communications · 2020 · 32 citations · 48 references

Concepts

Abstract

A novel hepatocyte-targeting fluorescent N<sub>2</sub>H<sub>4</sub> probe was first prepared. The probe can be used to image N<sub>2</sub>H<sub>4</sub> produced by the hydrolysis of isoniazid in HepG2 cells and the liver of zebrafish <italic>in situ</italic>.

References

48