MicroRNA-155 from sputum as noninvasive biomarker for diagnosis of active pulmonary tuberculosis.

Abstract

OBJECTIVES: , is a widespread infectious disease around the world. Early diagnosis is always important in order to avoid spreading. At present, many studies have confirmed that microRNA (miRNA) could be a useful tool for diagnosis. This study aimed to evaluate whether miRNAs could be regarded as a noninvasive diagnosis biomarker from sputum for pulmonary tuberculosis (PTB). MATERIALS AND METHODS: infection cell model. At last, the efficiency of other methods was compared with using miRNA. RESULTS: <0.05). CONCLUSION: Our research suggested that miR-155 may be an efficiency biomarker for active PTB diagnosis and bacteria-loads evaluation.